Under the My Company Menu, select Manage MiSP.
Click on the delete icon next to the selected MiSP.
Or select a new MiSP from the list. If you do this, the links to the current MiSP will not be cut until your new MiSP accepts your invitation.
Once a MiSP is removed (either by deleting them or by another MiSP accepting your request) it will cut all ties with them in iPaaS.com including removing any approved Role Shares.